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Therapies

Therapies — what each one is for, and where it fits in a protocol

Most of the therapies a longevity clinic offers are real, some are useful, and a few are mostly marketing. These pages say which is which — what each one is studied for, how strong the evidence is, who should avoid it, and where it sits next to the training, sleep and compound layers of a personal research protocol.

Reviewed by the Longevity Bros team · Updated 1 October 2026

Before you read onResearch and educational information for adults, not medical advice. This page describes what a therapy is studied for and where it can sit in a personal research protocol — it does not recommend it for you, and nothing here diagnoses, treats, cures or prevents any condition. Baseline labs come before anything, and your own physician has the final word. Longevity Bros offers coaching and written research protocols only — we do not sell, supply, source or ship any compound. The therapy itself is performed by licensed providers, and whether it belongs in your plan is a conversation with your physician.

A personal research protocol has layers: training, nutrition, sleep, labs, and — where the labs allow — the compound layer. Therapies are a sixth layer that people ask about constantly and that most sites either sell or ignore. We do neither. A coach can point to a sauna, a cold plunge, a hyperbaric chamber or a clinic session as something that fits a particular week of a plan; the session itself is performed by a licensed provider, and the decision to have it is yours and your physician's.

Each page below follows the same shape: what the therapy is, what the research actually shows (graded — randomised trial, meta-analysis, cohort, case series or mechanism-only), the protocols that have been studied, who it suits and who should avoid it, where it fits next to the rest of a protocol, an honest section on what is hype, and the questions we are asked most.

The eight therapies

How we grade the evidence

GradeWhat it meansExample on these pages
StrongMultiple randomised trials or a meta-analysis, consistent direction, clinically meaningful size.HBOT for diabetic foot ulcers and radiation injury.
ModerateRandomised trials exist but are small, short, or from one group; or a large cohort with plausible mechanism.Sauna and cardiovascular mortality; PRP for knee osteoarthritis.
EarlyPilot trials, case series, or a mechanism that has not yet been tested in people for that use.HBOT and telomere length; NAD+ infusions for "energy".
HypeThe marketed claim outruns anything that has been measured.Exosomes for ageing; cold plunges "burning fat".

The rule every page shares

Where to start

If you want the cheapest, best-evidenced lever first: sauna. If you are recovering from a hard block or a soft-tissue injury: hyperbaric oxygen and PRP, read next to the Wolverine page. If you are deciding whether a clinic's exosome or stem-cell offer is worth the money: read those two pages before you book anything, and bring the questions at the end of each to the clinic.

Your own protocol

Want these built into a plan for you?

Fifteen minutes of intake, a human-reviewed protocol within about 24 hours, three documents, a free coach call and check-ins through the cycle. €399, follow-up included. If a therapy on this page belongs in your plan, the protocol says where — and your physician says whether.

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